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Merck

DACT1

dishevelled-binding antagonist of beta-catenin 1

Synonyms:
DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
Species:
UniProtKB ID:
Gene ID:
  • Human(51339) Summary: The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(59036) dapper homolog 1, antagonist of beta-catenin (xenopus)
  • Rat(500666) dishevelled-binding antagonist of beta-catenin 1
  • Zebrafish(405799) dapper homolog 1, antagonist of beta-catenin (xenopus)
  • chicken(723789) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • domestic cat(101098146) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • cow(538778) dishevelled-binding antagonist of beta-catenin 1
  • dog(100687551) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • sheep(101116320) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • Domestic Rabbit(100339172) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • domestic guinea pig(100728819) dishevelled-binding antagonist of beta-catenin 1
  • naked mole-rat(101713951) dishevelled-binding antagonist of beta-catenin 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DACT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-DACT1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rat
Application
western blot
Anti-DACT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Dact1,
Species
mouse