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Merck

CBX1

chromobox homolog 1

Synonyms:
CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta
Species:
UniProtKB ID:
Gene ID:
  • Human(10951) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12412) chromobox 1
  • Rat(360609) chromobox homolog 1
  • naked mole-rat(101706928) chromobox homolog 1
  • domestic guinea pig(100716439) chromobox homolog 1
  • sheep(101116158) chromobox homolog 1
  • chicken(374237) chromobox homolog 1
  • domestic cat(101084070) chromobox homolog 1
  • cow(616506) chromobox homolog 1
  • dog(491051) chromobox homolog 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CBX1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat, yeast
Application
western blot
Anti-Cbx1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-CBX1/HP1-β antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-CBX1 antibody produced in mouse, clone 4E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CBX1,
Species
human