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Merck

APLP1

amyloid beta (A4) precursor-like protein 1

Synonyms:
APLP
Species:
UniProtKB ID:
Gene ID:
  • Human(333) Summary: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(11803) amyloid beta (A4) precursor-like protein 1
  • Rat(502317) amyloid beta (A4) precursor-like protein 1
  • Zebrafish(404233) amyloid beta (A4) precursor-like protein 1
  • dog(476478) amyloid beta (A4) precursor-like protein 1
  • Horse(100060016) amyloid beta (A4) precursor-like protein 1
  • cow(513154) amyloid beta (A4) precursor-like protein 1
  • domestic cat(101097529) amyloid beta (A4) precursor-like protein 1
  • sheep(101105352) amyloid beta (A4) precursor-like protein 1
  • domestic guinea pig(100725457) amyloid beta (A4) precursor-like protein 1
  • naked mole-rat(101706550) amyloid beta (A4) precursor-like protein 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-APLP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-APLP1 antibody produced in mouse, purified immunoglobulin,
Species Reactivity
human
Application
western blot
Anti-APLP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aplp1,
Species
mouse
MISSION® esiRNA, targeting human APLP1,
Species
human