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Merck

ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

Synonyms:
EST170205, MOAT-B, MOATB, MRP4
Species:
Human ABCC4 (10257), Mouse Abcc4 (239273), Rat Abcc4 (170924), Zebrafish abcc4 (368620), cow ABCC4 (616707), cow ABCC4 (515333), cow ABCC4 (617150), Horse ABCC4 (100050431), domestic cat ABCC4 (101096129), dog ABCC4 (485523) ...More
UniProtKB ID:
O15439, A9Z1Z7, Q8IVZ4, Q8IZN6, Q8NEW8, Q9Y6J2
Gene ID:
  • Human(10257) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(239273) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • Rat(170924) ATP-binding cassette, subfamily C (CFTR/MRP), member 4
  • Zebrafish(368620) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • cow(616707) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • cow(515333) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • cow(617150) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • Horse(100050431) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • domestic cat(101096129) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • dog(485523) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • chicken(418791) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • domestic guinea pig(100727718) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • naked mole-rat(101705542) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • sheep(101106534) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • Domestic Rabbit(100354688) ATP-binding cassette, sub-family C (CFTR/MRP), member 4

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0010257M3
Monoclonal Anti-ABCC4 antibody produced in mouse, clone 1B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB2500011
Anti-ABCC4/MRP4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
HPA002476
Anti-ABCC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Cell Lines

Product Number
Description
Species
MTOX1094
MRP4 Knockout Caco-2 Cells, one vial,
Species
human

Proteins

Product Number
Description
Species
SBVT07
SB-MRP4-HEK293, MRP4 human membrane vesicles,
Species
human

esiRNA

Product Number
Description
Species
EMU212521
MISSION® esiRNA, targeting mouse Abcc4,
Species
mouse
EHU030621
MISSION® esiRNA, targeting human ABCC4,
Species
human