- Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.
Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.
Science advances (2021-11-18)
Hongyu Ding, Zihong Chen, Katherine Wu, Shih Ming Huang, Warren L Wu, Sarah E LeBoeuf, Ray G Pillai, Joshua D Rabinowitz, Thales Papagiannakopoulos
PMID34788087
ABSTRACT
[Figure: see text].
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
L-Aspartic acid, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
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L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%
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Erastin, A cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality.
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Anti-NQO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution