1609002
USP
Salicylic acid
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
2-Hydroxybenzoic acid
About This Item
Recommended Products
grade
pharmaceutical primary standard
vapor density
4.8 (vs air)
vapor pressure
1 mmHg ( 114 °C)
API family
salicylic acid
manufacturer/tradename
USP
bp
211 °C (lit.)
mp
158-161 °C (lit.)
solubility
alcohol: freely soluble
benzene: slightly soluble
boiling water: soluble
chloroform: sparingly soluble
ether: freely soluble
toluene: slightly soluble
water: slightly soluble
density
1.44 g/cm3 at 20 °C
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
OC(=O)c1ccccc1O
InChI
1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChI key
YGSDEFSMJLZEOE-UHFFFAOYSA-N
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General description
Application
Also used to prepare standard solutions for the assay, impurity analysis, and performance test by using liquid chromatography in conjunction with a UV detector according to the given below monographs of United States Pharmacopeia (USP) :
- Salicylic Acid
- Methyl Salicylate
- Magnesium Salicylate Tablets
- Aspirin Boluses
Analysis Note
Other Notes
related product
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)
314.6 °F - closed cup
Flash Point(C)
157 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Protocols
Separation of Acetylsalicylic acid, analytical standard; Salicylic acid, BioXtra, ≥99.0%
Separation of Salicylic acid, meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance); Acetylsalicylic acid, purum, ≥99.0% (HPLC)
Separation of 4-Hydroxybenzoic acid; Acetylsalicylic acid; Benzoic acid; Salicylic acid; Ethyl 4-hydroxybenzoate
HPLC Analysis of Benzoic Acid Derivatives on Ascentis® C18
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