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P5739

Sigma-Aldrich

Placenta Growth Factor-2 from mouse

lyophilized powder, recombinant, expressed in baculovirus infected Sf21 cells, suitable for cell culture

Synonym(s):

PGF-2, PlGF-2

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About This Item

MDL number:
MFCD03458038
UNSPSC Code:
12352202
NACRES:
NA.77

biological source

mouse

Quality Level

200

recombinant

expressed in baculovirus infected Sf21 cells

Assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

~38 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P49764

storage temp.

−20°C

Gene Information

mouse ... Pgf(18654)

Biochem/physiol Actions

Angiogenic factor of the VEGF family. Ligand for the VEGFR-1 (flt-1) receptor and for neuropilin-1. PlGF-2 differs from PlGF-1 and PlGF-3 in having a heparin binding domain.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to bind to immobilized Flt1/Fc chimera in ELISA.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P280 - P305 + P351 + P338 - P310

Hazard Classifications

Skin Corr. 1A

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Articles

Vascular Endothelial Growth Factors (VEGF)

Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF-A (VEGF) is a potent growth factor for blood vessel endothelial cells, showing pleiotropic responses that facilitate cell migration, proliferation, tube formation, and survival. In the developing embryo VEGF-A mRNA is expressed by cells within tissues undergoing capillarization.

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