PHR1435

Warfarin Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium salt, 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
• Linear Formula: C₁₉H₁₅O₄Na
• CAS Number: 129-06-6
• Molecular Weight: 330.31
• EC Number: 204-929-4
• MDL number: MFCD00083223
• UNSPSC Code: 41116107
• PubChem Substance ID: 329822599
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP 672; traceable to Ph. Eur. W0100000; traceable to USP 1719000
• API family: warfarin
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Warfarin Sodium is an anticoagulant[1] rodenticide, commonly used for the control of rodents such as rats, mice, etc. in surroundings, commercial and industrial sites.[2][3]

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Warfarin Sodium may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using square-wave adsorptive cathodic stripping voltammetry.[1]

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA2743 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H300,H360,H412
• Precautionary Statements: P202 - P264 - P273 - P280 - P301 + P310 - P405
• Hazard Classifications: Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable