01-201
Heregulin-β3, Epidermal growth factor (EGF) domain
The Heregulin-β3 protein, Epidermal growth factor (EGF) domain is available in a 100 µg format.
Synonym(s):
EGF Domain
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
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Quality Level
form
liquid
manufacturer/tradename
Upstate®
technique(s)
cell culture | mammalian: suitable
input
sample type mesenchymal stem cell(s)
sample type cardiac stem cell(s)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... NRG1(3084)
General description
Product Source: Thrombin cleaved GST-fusion protein corresponding to the EGF domain (residues 178-241) of heregulin-beta 3.
Quality
Routinely evaluated by Receptor Activation Analysis.
Physical form
PBS with 30% glycerol. Liquid.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
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M Alimandi et al.
The EMBO journal, 16(18), 5608-5617 (1997-10-06)
Interleukin-3 (IL-3)-dependent murine 32D cells do not detectably express epidermal growth factor receptors (EGFRs) and do not proliferate in response to EGF, heregulin (HRG) or other known EGF-like ligands. Here, we report that EGF specifically binds to and can be
L M Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(12), 6809-6814 (1998-06-17)
Interleukin 3-dependent murine 32D cells do not detectably express members of the ErbB receptor family and do not proliferate in response to known ligands for these receptors. 32D transfectants were generated expressing human ErbB4 alone (32D.E4) or with ErbB2 (32D.E2/E4).
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