A-100

Anabasine-d₄ hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(s): (±) Anabasine-d₄ HCl solution
• Empirical Formula (Hill Notation): C₁₀D₄H₁₁ClN₂
• Molecular Weight: 202.72
• EC Number: 200-659-6
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol (as free base)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• InChI: 1S/C10H14N2.ClH/c1-2-7-12-10(5-1)9-4-3-6-11-8-9;/h3-4,6,8,10,12H,1-2,5,7H2;1H/i3D,4D,6D,8D;
• InChI key: VTMZQNZVYCJLGG-BHBAGPQMSA-N

Description

General description

Anabasine is a nicotine alkaloid present in tobacco products and used as an indicator of smoking or tobacco use. This certified Snap-N-Spike^® Solution is suitable for use as an internal standard for quantification of anabasine levels in urine or other matrices for nicotine testing or environmental monitoring applications by LC-MS/MS or GC/MS.

Application

• Anabasine-d₄ hydrochloride stable isotope-labeled compound: A study on mesoporous titanium nanoparticles loaded with berberine hydrochloride explores UV-triggered drug release, demonstrating the utility of Anabasine-d₄ hydrochloride in enhancing antibiotic delivery and efficacy, especially in bacterial infections (Zuo et al., 2024).


• High purity Anabasine-d₄ hydrochloride for analytical research: Research on berberine hydrochloride-loaded liposomes-in-gel assesses antioxidant activity and eczema treatment, with Anabasine-d₄ hydrochloride playing a critical role in stabilizing formulations and improving therapeutic outcomes (Shen et al., 2024).


• Anabasine-d₄ HCl solution for nicotine receptor studies: Anabasine-d₄ hydrochloride is highlighted in a study on synthetic routes and clinical applications of small-molecule EGFR inhibitors for cancer therapy, emphasizing its importance in oncological research and receptor interaction studies (Wang et al., 2024).


• Deuterated Anabasine hydrochloride for mass spectrometry: A publication on poly(lactic-co-glycolic acid) nanoparticles investigates drug release behaviors co-loaded with hydrophilic and hydrophobic drugs, where Anabasine-d₄ hydrochloride is crucial as an internal standard in mass spectrometry to ensure accurate pharmacokinetic profiles (Wang et al., 2024).


• Anabasine-d₄ as an internal standard in pharmacokinetic analysis: Anabasine-d₄ hydrochloride′s role as an internal standard is underscored in a study on the pharmacokinetics of traditional Chinese medicine in treating primary Sjögren syndrome, providing insights into complex bioanalytical methodologies (Chen et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup