Skip to Content
Merck
All Photos(1)

Documents

513253

Sigma-Aldrich

N-Methoxy-N-methylacetamide

98%

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3CON(OCH3)CH3
CAS Number:
Molecular Weight:
103.12
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

refractive index

n20/D 1.426 (lit.)

bp

152 °C (lit.)

density

0.97 g/mL at 25 °C (lit.)

SMILES string

CON(C)C(C)=O

InChI

1S/C4H9NO2/c1-4(6)5(2)7-3/h1-3H3

InChI key

OYVXVLSZQHSNDK-UHFFFAOYSA-N

General description

Simple Weinreb amide used in the synthesis of marine natural products myriaporone and usneoidone as a ketone synthon.

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

120.2 °F - closed cup

Flash Point(C)

49 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Total synthesis of natural myriaporones.
Marta Pérez et al.
Angewandte Chemie (International ed. in English), 43(13), 1724-1727 (2004-03-24)
Asymmetric synthesis of heterocycles using sulfinimines (N-sulfinyl imines).
Davis FA, et al.
ARKIVOC (Gainesville, FL, United States), 7, 120-128 (2006)
European Journal of Organic Chemistry, 9, 1911-1922 (2004)
Acetylations of strongly basic and nucleophilic enolate anions with N-methoxy-N-methylacetamide.
Oster TA and Harris TM.
Tetrahedron Letters, 24(18), 1851-1854 (1983)
Xue Zhi Zhao et al.
Bioorganic & medicinal chemistry, 14(23), 7816-7825 (2006-08-16)
The diketo acid (DKA) class of HIV-1 integrase inhibitors are thought to function by chelating divalent metal ions within the enzyme catalytic center. However, differences in mutations conferring resistance among sub-families of DKA inhibitors suggest that multiple binding orientations may

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service