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Merck

STAT4

signal transducer and activator of transcription 4

Synonyms:
SLEB11
Species:
UniProtKB ID:
Gene ID:
  • Human(6775) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
  • Mouse(20849) signal transducer and activator of transcription 4
  • Rat(367264) signal transducer and activator of transcription 4
  • Zebrafish(368519) signal transducer and activator of transcription 4
  • chicken(768406) signal transducer and activator of transcription 4
  • dog(478845) signal transducer and activator of transcription 4
  • domestic cat(101080650) signal transducer and activator of transcription 4
  • Horse(100054693) signal transducer and activator of transcription 4
  • domestic guinea pig(100726892) signal transducer and activator of transcription 4
  • Domestic Rabbit(100344146) signal transducer and activator of transcription 4
  • naked mole-rat(101718558) signal transducer and activator of transcription 4
  • cow(515988) signal transducer and activator of transcription 4
  • sheep(101117562) signal transducer and activator of transcription 4

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ELISA

Product Number
Description
Species
Phosphotyrosine STAT4 / Signal Transducer and Activator of Transcription 4 ELISA Kit, ,
Species
human
Cell-Based ELISA for detecting phospho-STAT4 (pTyr693) in cultured cell lines, 192 assays,
Species
mouse, human
Cell-Based ELISA for detecting phospho-STAT4 (pTyr693) in cultured cell lines, 96 assays,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-STAT4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-phospho-STAT4 (pTyr693) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-STAT4 (Ab-693) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-STAT4 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, horse, human, pig, rabbit
Application
immunohistochemistry
western blot
Anti-STAT4 Antibody, clone 10H10O9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunoprecipitation (IP)

western blot

Proteins

Product Number
Description
Species
STAT4 human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human STAT4,
Species
human
MISSION® esiRNA, targeting mouse Stat4,
Species
mouse