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Merck

LMAN1

lectin, mannose-binding, 1

Synonyms:
ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Species:
UniProtKB ID:
Gene ID:
  • Human(3998) Summary: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq, Jul 2008]
  • Mouse(70361) lectin, mannose-binding, 1
  • Rat(116666) lectin, mannose-binding, 1
  • Zebrafish(559775) lectin, mannose-binding, 1
  • chicken(426849) lectin, mannose-binding, 1
  • cow(511649) lectin, mannose-binding, 1
  • Horse(100050262) lectin, mannose-binding, 1
  • domestic cat(101080833) lectin, mannose-binding, 1
  • dog(476186) lectin, mannose-binding, 1
  • sheep(101117293) lectin, mannose-binding, 1
  • Domestic Rabbit(100354112) lectin, mannose-binding, 1
  • domestic guinea pig(100728262) lectin, mannose-binding, 1
  • naked mole-rat(101723407) lectin, mannose-binding, 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LMAN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ERGIC-53 antibody, Mouse monoclonal, clone ERGIC-3, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LMAN1,
Species
human
MISSION® esiRNA, targeting mouse Lman1,
Species
mouse
MISSION® esiRNA, targeting mouse Lman1,
Species
mouse