HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
Synonyms:
Species:
Human HMGCS2 (3158), Mouse Hmgcs2 (15360), Rat Hmgcs2 (24450), Goat HMGCS2 (100860890), Domestic Rabbit HMGCS2 (100343479), sheep HMGCS2 (101111590), domestic guinea pig Hmgcs2 (100727078), naked mole-rat Hmgcs2 (101712063), chicken HMGCS2 (424380), dog HMGCS2 (607923) ...More
UniProtKB ID:
Gene ID:
- Human(3158) Summary: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
- Mouse(15360) 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
- Rat(24450) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- Goat(100860890) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- Domestic Rabbit(100343479) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- sheep(101111590) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- domestic guinea pig(100727078) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- naked mole-rat(101712063) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- chicken(424380) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- dog(607923) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- domestic cat(101088768) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- cow(503684) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- Horse(100059971) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-HMGCS2, (C-terminal) antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-HMGCS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HMGCS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-HMGCS2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-HMGCS2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, human, mouse, rabbit, rat
Application
western blot