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GPX1

glutathione peroxidase 1

Synonyms:
GPXD, GSHPX1
Species:
UniProtKB ID:
Gene ID:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GPX1 Antibody, clone 1J19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
canine, feline, human, monkey, porcine
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal ANTI-FLAG® M2-Peroxidase (HRP) antibody produced in mouse, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
all
Application
ELISA
Anti-Gpx1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, mouse, rat
Application
ELISA
western blot
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
alligator, human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, pig
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GPX1,
Species
human