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  • Perinatal multiple exposure to neurotoxic (lead, methylmercury, ethylmercury, and aluminum) substances and neurodevelopment at six and 24 months of age.

Perinatal multiple exposure to neurotoxic (lead, methylmercury, ethylmercury, and aluminum) substances and neurodevelopment at six and 24 months of age.

Environmental pollution (Barking, Essex : 1987) (2014-02-04)
Rejane C Marques, José V E Bernardi, José G Dórea, Maria de Fatima R Moreira, Olaf Malm
ABSTRACT

We studied neurodevelopment in infants from two communities. Children living in the vicinity of tin-ore kilns and smelters - TOKS; n = 51) were compared to children from a fishing village (Itapuã; n = 45). Mean hair-Hg (HHg) concentrations were significantly higher in Itapuã children which received significantly (p = 0.0000001) less mean ethylmercury (88.6 μg) from Thimerosal-containing vaccines (TCV) than the TOKS children (120 μg). Breast-milk Pb concentrations were significantly higher in the TOKS mothers (p = 0.000017; 10.04 vs. 3.9 μg L(-1)). Bayley mental development index (MDI) and psychomotor development index (PDI) were statistically significant (respectively p < 0.0000001, p = 0.000007) lower for the TOKS children only at 24 months of age. Multivariate regression analysis showed that MDI was negatively affected by breast-milk Pb and by HHg. PDI was positively affected by breastfeeding and negatively affected by ethylmercury. Milestone achievements were negatively affected by breast-milk Pb (age of walking) and by HHg (age of talking).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Aluminum, powder, ≥91% (complexometric)
Sigma-Aldrich
Aluminum, evaporation slug, diam. × L 6.3 mm × 6.3 mm, 99.999% trace metals basis
Aluminum, IRMM®, certified reference material, 1.0 mm foil
Aluminum, IRMM®, certified reference material, 1.0 mm wire
Aluminum, honeycomb, 300x300mm, thickness 26.5mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), facing skin aluminum 0.55mm, 99.9%
Aluminum, honeycomb, 300x300mm, thickness 52.3mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), facing skin glass fiber 0.75mm, 99.9%
Aluminum, honeycomb, 300x300mm, thickness 26.5mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), facing skin carbon fiber / epoxy, 99.9%
Aluminum, honeycomb, 300x300mm, thickness 5mm, cell size 13mm, cell wall 0.1mm, core density 0.062g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, honeycomb, 600x600mm, thickness 5mm, cell size 3.2mm, cell wall 0.025mm, core density 0.072g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, honeycomb, 300x300mm, thickness 13.9mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), facing skin aluminum 0.55mm, 99.9%
Aluminum, honeycomb, 600x600mm, thickness 20mm, cell size 3.2mm, cell wall 0.025mm, core density 0.072g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, foam, 150x150mm, thickness 6.35mm, bulk density 0.2g/cm3, porosity 0.93, 8 pores/cm, aluminum 6101 grade, 98.5%
Aluminum, foam, 150x150mm, thickness 30mm, bulk density 0.2g/cm3, porosity 0.93, aluminum 6101 grade, 98.5%
Aluminum, honeycomb, 600x600mm, thickness 26.5mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), facing skin carbon fiber / epoxy, 99.9%
Aluminum, honeycomb, 300x300mm, thickness 10mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, honeycomb, 300x300mm, thickness 20mm, cell size 4.8mm, cell wall 0.038mm, core density 0.070g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, honeycomb, 600x600mm, thickness 10mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, honeycomb, 600x600mm, thickness 52.3mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), facing skin glass fiber 0.75mm, 99.9%
Aluminum, foam, 150x150mm, thickness 6.35mm, bulk density 0.2g/cm3, porosity 0.93, 2 pores/cm, aluminum 6101 grade, 98.5%
Aluminum, honeycomb, 600x600mm, thickness 5mm, cell size 13mm, cell wall 0.1mm, core density 0.062g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, honeycomb, 300x300mm, thickness 5mm, cell size 19mm, cell wall 0.064mm, core density 0.029g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, mesh, 900x900mm, nominal aperture 0.38mm, wire diameter 0.25mm, 40x40 wires/inch, open area 37%, plain weave mesh
Aluminum, insulated wire, 2m, conductor diameter 0.1mm, insulation thickness 0.005mm, polyimide insulation, 99.95+%
Aluminum, microleaf disks, 25mm, thinness 0.15μm, specific density 41.28μg/cm2, removable support, 99.999%
Aluminum, microleaf disks, 25mm, thinness 0.25μm, specific density 68.8μg/cm2, removable support, 99.999%
Aluminum, microleaf disks, 25mm, thinness 0.5μm, specific density 120.6μg/cm2, removable support, 99.999%
Aluminum, microleaf disks, 25mm, thinness 1.0μm, specific density 269.9μg/cm2, removable support, 99.999%
Aluminum, tube, 0.1m coil, as drawn, outside diameter 0.30mm, inside diameter 0.2mm, wall thickness 0.05mm, 99.5%
Aluminum, insulated wire, 20m, conductor diameter 0.1mm, insulation thickness 0.005mm, polyimide insulation, 99.95+%
Aluminum, mesh, 150x150mm, nominal aperture 0.38mm, wire diameter 0.25mm, 40x40 wires/inch, open area 37%, plain weave mesh