Glycobiology Profiling Tools

Related Resources

• Article: How to Improve Glycoform and Glycopeptide for Mucin Preparations
• Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin
• Article: Glycosaminoglycans and Proteoglycans

  There are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain.

• Article: Glycosyltransferases

  Glycosyltransferases were initially considered to be specific for a single glycosyl donor and acceptor, which led to the one enzyme-one linkage concept. Subsequent observations have refuted the theory of absolute enzymatic specificity by describing the transfer of analogs of some nucleoside mono- or diphosphate sugar donors.

• Article: What is Hyaluronan?

  Hyaluronan is a major component of the extracellular matrix. It’s the simplest glycosaminoglycan, and it plays several biological roles.

• Article: Sialic Acid
• Article: Glycobiology - Carbohydrate Enzymes and Proteins

  Explore our complex carbohydrate proteins, enzyme products and kits for investigating oligosaccharides, polysaccharides, and numerous additional aspects of your carbohydrate workflow.

• Article: Glycosphingolipids

  Glycosphingolipids

• Article: Glycosyltransferases: Tools for Synthesis and Modification of Glycans

  The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist.

• Article: N-Linked Glycan Strategies

  Explore various strategies for deglycosylating N-linked glycans involving PNGase F, PNGase A (Glycopeptidase A), and even native and sequential deglycosylation with endoglycosidases like Endoglycosidase H, Endoglycosidase F, and exoglycosidases.

• Article: O-Linked Glycan Strategies

  Learn about O-linked glycan strategies, such as the actions of O-glycosidase, how to remove di and trisialylation sialic acid residues, β-linked galactose, and N-acetylglucosamine, as well as other O-glycan modifications.

• Article: Glycoprofile™ Labeling Kits

  Glycoprofile Labeling Kits for Glycan Analysis designed for efficient labeling of N-linked, O-linked and glycosylphosphatidylinositol (GPI) anchored glycans using your choice of 2-aminobenzamide (2-AB) or 2-aminobenzoic acid (anthranilic acid; 2-AA) 1,2

• Article: Deglycosylation Kits

  Deglycosylation Kits

• Glycan Labeling

  Structural modifications of proteins are essential to living cells. When aberrantly regulated they are often the basis of disease. Glycans are responsible for much of the structural variation in biologic systems, and their representation on cell surfaces is commonly called the “glycome.”

• Article: Mass Spectrometry of Glycans

  The development of modern mass spectrometry (MS) equipment with high resolution and mass accuracy has led to its use in analyzing glycans for both profiling and structural studies.

• Article: HPLC Analysis of Glycans

  HPLC Analysis of Glycans