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P8759

Sigma-Aldrich

Pyrogallol Red

Powder

Synonym(s):

Pyrogallolsulfonephthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12O8S
CAS Number:
32638-88-3
Molecular Weight:
400.36
Beilstein:
61394
EC Number:
251-134-3
MDL number:
MFCD00005046
UNSPSC Code:
12171500
PubChem Substance ID:
24898975
NACRES:
NA.47

product name

Pyrogallol Red, Suitable for use as a complexometric indicator

Quality Level

200

form

powder

technique(s)

titration: suitable

color

green to very dark green, and brown

mp

≥300 °C (lit.)

solubility

1 M NH4OH: 10 mg/mL, clear

εmax

≥450 at 475 nm in methanol

suitability

suitable for complexometric indicator

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc2c(Oc3c(O)c(O)ccc3C24OS(=O)(=O)c5ccccc45)c1O

InChI

1S/C19H12O8S/c20-12-7-5-10-17(15(12)22)26-18-11(6-8-13(21)16(18)23)19(10)9-3-1-2-4-14(9)28(24,25)27-19/h1-8,20-23H

InChI key

KUQNCHZOCSYKOR-UHFFFAOYSA-N

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General description

Pyrogallol red (PGR) is an ortho-diphenolic dye. It has high reactivity towards reactive oxygen species (ROS) and reactive nitrogen species (RNS) that include peroxynitrite, radical, peroxyl radicals, hypochlorite & superoxide anion.

Application

Pyrogallol Red is suitable to prepare Fujita and Watanabe dye reagent used in Pyrogallol Red-Molybdenum (IV) complex (PR) method for the determination and quantification of urinary proteins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K de Leeuw et al.
Journal of critical care, 36, 200-206 (2016-11-05)
In patients with severe burns, resuscitation with large volumes of fluid is needed, partly because of an increase in capillary leakage. Corticosteroids might be beneficial by diminishing capillary leakage. This study aimed to assess in severely burned nonseptic patients whether
Tuula K Outinen et al.
Infectious diseases (London, England), 49(11-12), 840-846 (2017-08-02)
Puumala hantavirus (PUUV) causes haemorrhagic fever with renal syndrome characterized by thrombocytopenia, capillary leakage and acute kidney injury (AKI) with proteinuria and haematuria. Although the typical histologic lesion is acute tubulointerstitial nephritis, the amount of glomerular proteinuria predicts the severity
Extent of aminoglycoside interference in the pyrogallol red-molybdate protein assay depends on the concentration of sodium oxalate in the dye reagent
Marshall Thomas
Clinical Chemistry (2004)
K Janšáková et al.
Physiological research, 68(3), 467-479 (2019-03-25)
Thermally processed food contains advanced glycation end products (AGEs) including N(epsilon)-(carboxymethyl)lysine (CML). Higher AGEs or circulating CML were shown to be associated with pregnancy complications such as preeclampsia and gestational diabetes. It is unclear whether this association is causal. The
Jian Sun et al.
Life sciences, 76(24), 2849-2860 (2005-04-06)
In the current study, we compared purified Salvia miltiorrhiza extract (PSME) with Angiotensin-converting enzyme inhibitor, Ramipril, in in vitro experiments and also in vivo using animal model of myocardial infarction. PSME was found to have a significantly higher trolox equivalent
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