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14-303-M

Sigma-Aldrich

MKK6/SKK3 Protein, active, 10 µg

Active, N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. For use in Kinase Assays.

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About This Item

UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.32

biological source

human

Quality Level

mol wt

Mw 82 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

Gene Information

human ... MAP2K6(5608)

General description

N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end.
Product Source: Expressed in E. coli

Biochem/physiol Actions

Protein Target: MKK6
Target Sub-Family: STE

Quality

Routinely evaluated by phosphorylation of unactive p38α/SAPK2a.

Physical form

Amylose Resin Beads

Storage and Stability

6 months at -70°C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R Meier et al.
European journal of biochemistry, 236(3), 796-805 (1996-03-15)
The identities of the upstream activators of the mitogen-activated protein (MAP) kinase homologues termed stress-activated-protein (SAP) kinase-1 (also known as JNK or SAPK) and SAP kinase-2 (also known as p38, RK and CSBP) were investigated in rat PC12 cells and
M Goedert et al.
The EMBO journal, 16(12), 3563-3571 (1997-06-01)
A cDNA was cloned that encodes human stress-activated protein kinase-4 (SAPK4), a novel MAP kinase family member whose amino acid sequence is approximately 60% identical to that of the other three SAP kinases which contain a TGY motif in their

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