713589

p-Toluenesulfonyl azide solution

11-15 % (w/w) in toluene, 97%

• Synonym(s): 4-Methylbenzenesulfonyl azide solution, p-Toluenesulfonazide solution, Tosyl azide solution
• Empirical Formula (Hill Notation): C₇H₇N₃O₂S
• CAS Number: 941-55-9
• Molecular Weight: 197.21
• MDL number: MFCD00180767
• UNSPSC Code: 12352125
• PubChem Substance ID: 329763205
• NACRES: NA.22

Properties

• Assay: ≥96.5% (HPLC); 97%
• form: liquid
• concentration: 11-15 % (w/w) in toluene
• refractive index: n20/D 1.502
• density: ~0.90 g/mL at 20 °C
• storage temp.: 2-8°C
• SMILES string: Cc1ccc(cc1)S(=O)(=O)N=[N+]=[N-]
• InChI: 1S/C7H7N3O2S/c1-6-2-4-7(5-3-6)13(11,12)10-9-8/h2-5H,1H3
• InChI key: NDLIRBZKZSDGSO-UHFFFAOYSA-N

Description

General description

p-Toluenesulfonyl azide is used as a nitrene source and in the synthesis of N-sulfimines, N-tosylphosphinimines, and N-sulfoximines.

Application

p-Toluenesulfonyl azide solution can be employed as a reagent along with alkyne, and amine in the three-component coupling reaction for the synthesis of N-sulfonylamidines in presence of copper catalyst.
It can also be used in the synthesis of N-sulfonyl-1,2,3-triazoles by azide-alkyne cycloaddition reaction in the presence of copper catalyst.

Modifier of refractive index changes of transparent PMMA to generate permanent patterns in films

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H300,H304,H315,H336,H361d,H373,H412
• Precautionary Statements: P201 - P210 - P273 - P301 + P310 - P303 + P361 + P353 - P331
• Hazard Classifications: Acute Tox. 2 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 39.2 °F - closed cup - Solvent
• Flash Point(C): 4.0 °C - closed cup - Solvent
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves