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Merck

YTHDF2

YTH domain family, member 2

Synonyms:
HGRG8, NY-REN-2
Species:
UniProtKB ID:
Gene ID:
  • Human(51441) Summary: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]
  • Mouse(213541) YTH domain family 2
  • Rat(313053) YTH domain family, member 2
  • chicken(419583) YTH domain family, member 2
  • dog(478161) YTH domain family, member 2
  • domestic cat(101088596) YTH domain family, member 2
  • domestic guinea pig(100733512) YTH domain family, member 2
  • naked mole-rat(101721610) YTH domain family, member 2
  • Domestic Rabbit(100351518) YTH domain family, member 2
  • cow(541050) YTH domain family, member 2
  • sheep(101122840) YTH domain family, member 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-YTHDF2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-YTHDF2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunocytochemistry
western blot
Anti-YTHDF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-YTHDF2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, zebrafish
Application
western blot
Anti-YTHDF2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, horse, human, mouse, rabbit, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human YTHDF2,
Species
human
MISSION® esiRNA, targeting mouse Ythdf2,
Species
mouse