Skip to Content
Merck

NTRK2

neurotrophic tyrosine kinase, receptor, type 2

Synonyms:
GP145-TrkB, TRKB, trk-B
Species:
UniProtKB ID:
Gene ID:
  • Human(4915) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18212) neurotrophic tyrosine kinase, receptor, type 2
  • Rat(25054) neurotrophic tyrosine kinase, receptor, type 2
  • sheep(101116015) neurotrophic tyrosine kinase, receptor, type 2
  • Domestic Rabbit(100352548) neurotrophic tyrosine kinase, receptor, type 2
  • naked mole-rat(101720037) neurotrophic tyrosine kinase, receptor, type 2
  • domestic guinea pig(100723565) neurotrophic tyrosine kinase, receptor, type 2
  • chicken(396157) neurotrophic tyrosine kinase, receptor, type 2
  • cow(505824) neurotrophic tyrosine kinase, receptor, type 2
  • Horse(100061700) neurotrophic tyrosine kinase, receptor, type 2
  • domestic cat(101101347) neurotrophic tyrosine kinase, receptor, type 2
  • dog(484147) neurotrophic tyrosine kinase, receptor, type 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Phosphotyrosine NTRK2 / BDNF/NT-3 Growth Factors Receptor ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NTRK2 antibody produced in mouse, clone 4D3-F10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-phospho-NTRK2 (pTyr705) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-NTRK2 antibody produced in mouse, clone 3D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-phospho-TrkB (Tyr816) Antibody, clone 2C21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, mouse, rat, sheep
Application
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB, serum, Chemicon®,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
TRKB (455-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
TrkB/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human
NTRK2/TRKB human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
TrkB Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, human TrkB, amino acids 455-end, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NTRK2,
Species
human
MISSION® esiRNA, targeting mouse Ntrk2,
Species
mouse
MISSION® esiRNA, targeting mouse Ntrk2,
Species
mouse