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Merck

NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Synonyms:
H2TF1, LYT-10, LYT10, NF-kB2, p105, p52
Species:
UniProtKB ID:
Gene ID:
  • Human(4791) Summary: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, May 2012]
  • Mouse(18034) nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
  • Rat(309452) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
  • Zebrafish(415100) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
  • chicken(386574) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
  • domestic cat(101080578) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
  • cow(526392) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
  • dog(486858) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
  • naked mole-rat(101714147) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
  • domestic guinea pig(100715820) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NFKB2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8266, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NF-κB2 Antibody, clone 4K3V3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-NF-κB p100 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-NFKB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-NFKB2 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride, ≥96% (TLC), powder,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Caffeic acid phenethyl ester, ≥97% (HPLC), powder,
Species
human

Proteins

Product Number
Description
Species
NFKB2 (1-454), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nfkb2,
Species
mouse
MISSION® esiRNA, targeting human NFKB2,
Species
human