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Merck

HAVCR2

hepatitis A virus cellular receptor 2

Synonyms:
HAVcr-2, KIM-3, TIM3, TIMD-3, TIMD3, Tim-3
Species:
Human HAVCR2 (84868), Mouse Havcr2 (171285), Rat Havcr2 (363578), dog HAVCR2 (479318), domestic cat HAVCR2 (101089981), cow HAVCR2 (768047), sheep HAVCR2 (101112135)
UniProtKB ID:
Q8TDQ0, B2RAY2, Q8WW60, Q96K94
Gene ID:
  • Human(84868) Summary: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
  • Mouse(171285) hepatitis A virus cellular receptor 2
  • Rat(363578) hepatitis A virus cellular receptor 2
  • dog(479318) hepatitis A virus cellular receptor 2
  • domestic cat(101089981) hepatitis A virus cellular receptor 2
  • cow(768047) hepatitis A virus cellular receptor 2
  • sheep(101112135) hepatitis A virus cellular receptor 2

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ELISA

Product Number
Description
Species
RAB1087
Human TIM-3 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
ZRB2978
Anti-TIM-3/HAVCR2 Antibody, clone 2B7-L1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
MABF62
Anti-Tim3 Antibody, clone 2E2, clone 2E2, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot
MABF230
Anti-TIM-3, clone RMT3-23, Azide Free Antibody, clone RMT3-23, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
MABF73
Anti-Tim3 Antibody, clone 5D12, clone 5D12, from mouse,
Species Reactivity
mouse
Application
flow cytometry
SAB2501040
Anti-TIM3/HAVCR2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry
immunofluorescence
western blot

Proteins

Product Number
Description
Species
SRP0590
TIM-3, Biotin Labeled, His-Tag, recombinant, expressed in HEK 293 cells,
Species
human
SRP8055
Tim-3 (human): FC (human), recombinant, expressed in CHO cells, ≥98% (SDS-PAGE),
Species
human
SRP8056
Tim-3 (mouse): FC (human), recombinant, expressed in CHO cells, ≥98% (SDS-PAGE),
Species
mouse
SRP0566
TIM-3, FLAG® -Tag, recombinant, expressed in HEK 293 cells,
Species
human

esiRNA

Product Number
Description
Species
EMU219281
MISSION® esiRNA, targeting mouse HAVCR2,
Species
mouse
EHU037081
MISSION® esiRNA, targeting human HAVCR2,
Species
human