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Merck

ARFGEF1

ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

Synonyms:
ARFGEP1, BIG1, P200
Species:
UniProtKB ID:
Gene ID:
  • Human(10565) Summary: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Aug 2011]
  • Mouse(211673) ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
  • Rat(312915) ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
  • sheep(101102247) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
  • naked mole-rat(101698432) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
  • domestic guinea pig(100714174) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
  • Zebrafish(100329953) ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
  • chicken(420170) ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
  • cow(281022) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
  • Horse(100063272) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
  • domestic cat(101092584) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
  • dog(477903) ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BIG1 Antibody, clone 102, clone 102, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot
Anti-ARFGEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ARFGEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ARFGEF1, affinity isolated antibody,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ARFGEF1,
Species
human
MISSION® esiRNA, targeting mouse Arfgef1,
Species
mouse