Skip to Content
Merck

ACVRL1

activin A receptor type II-like 1

Synonyms:
ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Species:
UniProtKB ID:
Gene ID:
  • Human(94) Summary: This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
  • Mouse(11482) activin A receptor, type II-like 1
  • Rat(25237) activin A receptor type II-like 1
  • Zebrafish(266753) activin A receptor type II-like 1
  • domestic cat(101097406) activin A receptor type II-like 1
  • cow(534536) activin A receptor type II-like 1
  • Horse(100061313) activin A receptor type II-like 1
  • domestic cat(100135773) activin A receptor type II-like 1
  • dog(477603) activin A receptor type II-like 1
  • chicken(100857446) activin A receptor type II-like 1
  • sheep(101114095) activin A receptor type II-like 1
  • domestic guinea pig(100716392) activin A receptor type II-like 1
  • naked mole-rat(101709807) activin A receptor type II-like 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ACVRL1 antibody produced in mouse, clone 5B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-ACVRL1 antibody produced in mouse, clone 7H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-ACVRL1 antibody produced in mouse, clone 1E7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-ACVRL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACVRL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human
Application
western blot

Proteins

Product Number
Description
Species
Activin Receptor-Like Kinase 1/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACVRL1,
Species
human
MISSION® esiRNA, targeting mouse Acvrl1,
Species
mouse