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Key Documents

SAB4503345

Sigma-Aldrich

Anti-ZNF397 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

ZNF397, ZNF47, Zinc finger and SCAN domain-containing protein 15, Zinc finger protein 397, Zinc finger protein 47

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 61 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
western blot: 1:500-1:1000

NCBI accession no.

Q8NF99

UniProt accession no.

Q8NF99

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ZNF397(84307)

General description

Zinc finger protein 397 (ZNF397) belongs to the Cys2His2 group of the zinc-finger superfamily. It possesses a leucine-rich SCAN domain and nine Cys2His2 zinc fingers. The gene encoding this protein is localized on human chromosome 18q12.

Immunogen

The antiserum was produced against synthesized peptide derived from human ZNF397.

Immunogen Range: 10-59

Biochem/physiol Actions

Zinc finger protein 397 (ZNF397) has been shown to co-localize with centromere protein-A (CENP-A) during early prophase and interphase. It might be involved in transcriptional regulation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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S L Bailey et al.
Chromosoma, 117(4), 367-380 (2008-03-29)
The centromere is a complex structure required for equal segregation of newly synthesised sister chromatids at mitosis. One of the significant objectives in centromere research is to determine the complete repertoire of protein components that constitute the kinetochore. Here, we
Yimin Wu et al.
Gene, 310, 193-201 (2003-06-13)
We have identified two novel human SCAN domain genes ZNF396 and ZNF397, which are clustered within the region of chromosome 18q12. Three isoforms of ZNF396 transcript, 1.5, 2.5 and 3.9-kb, are expressed highly in liver. Four isoforms of ZNF397 transcript

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