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EMU022811

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Iws1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGAAGATTCGGGAGGAATTGTTAAAGATTCTGCAAGAGCTACCTAGTGTGAGCCAAGAGACCCTGAAGCATAGTGGGATTGGCCGAGCAGTGATGTATCTGTATAAACACCCTAAGGAATCAAGGTCCAACAAGGATATGGCAGGGAAGCTCATCAATGAGTGGTCTCGGCCCATATTTGGTCTTACCTCAAACTATAAAGGAATGACAAGAGAAGAAAGGGAACAGAGAGATCTAGAACAAATGCCACAGCGACGAAGATTGAGCAGCACTGGTGGTCAGACACCACGAAGAGACCTGGAGAAGGTCCTAACAGGAGAAGAAAAGGCTCTTAGACCTGGAGATCCTGGCTTCTGTGCCCGTGCAAGAGTCCCAATGCCATCAAACAAGGACTATGTTGTCAGGCCCAAGTGGAATGTAGAAATGGAGTCATCCAGGTTTCAGGCAT

Ensembl | mouse accession no.

ENSMUSG00000024384

NCBI accession no.

NM_173441

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... IWS1(73473) , Iws1(73473)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Reza K Oqani et al.
Scientific reports, 9(1), 3831-3831 (2019-03-09)
The mRNA processing and export factor, Iws1, interacts with the histone H3/H4 chaperone, Spt6 (Supt6 in mouse gene ontology) and recruits the lysine methyltransferase, Setd2, to chromatin to regulate H3K36me3. This recruitment is known to be crucial for pre-mRNA splicing

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