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Key Documents

B0990000

Betahistine mesilate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Betahistine mesylate

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About This Item

Empirical Formula (Hill Notation):
C8H12N2 · 2CH4O3S
CAS Number:
Molecular Weight:
328.41
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

betahistine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C8H12N2.2CH4O3S/c1-9-7-5-8-4-2-3-6-10-8;2*1-5(2,3)4/h2-4,6,9H,5,7H2,1H3;2*1H3,(H,2,3,4)

InChI key

ZBJJDYGJCNTNTH-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betahistine mesilate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Isilay Oz et al.
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Otto R Maarsingh et al.
The British journal of general practice : the journal of the Royal College of General Practitioners, 62(603), 518-520 (2012-12-26)
Adriana Pontin Garcia et al.
Brazilian journal of otorhinolaryngology, 79(3), 366-374 (2013-06-08)
Virtual reality technology can provide a wide range of sensory stimuli to generate conflicts of varying degrees of complexity in a safe environment. To verify the effect of a virtual realitybased balance rehabilitation program for patients with Menière's disease. This
R Gürkov et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(4), 1231-1235 (2012-07-05)
This study aimed to assess whether standard-dose Betahistine (48 mg daily) exerts an effect upon the degree of endolymphatic hydrops in patients with Menière's disease using a retrospective case series in the setting of a tertiary neurotology referral centre. In
Fritz Ihler et al.
PloS one, 7(6), e39086-e39086 (2012-06-30)
Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the effect of betahistine on guinea pigs at

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