S-033
JWH-018 5-Pentanoic acid metabolite solution
100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
JWH-018 5-Pentanoic acid
About This Item
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in methanol
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
forensics and toxicology
forensics and toxicology
format
single component solution
storage temp.
−20°C
SMILES string
O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCC(O)=O)C4=C3C=CC=C4
InChI
1S/C24H21NO3/c26-23(27)14-5-6-15-25-16-21(19-11-3-4-13-22(19)25)24(28)20-12-7-9-17-8-1-2-10-18(17)20/h1-4,7-13,16H,5-6,14-15H2,(H,26,27)
InChI key
BYIVGHIYNFQIJX-UHFFFAOYSA-N
General description
Application
- Advanced Mass Spectrometry Techniques: JWH-018 has been utilized in pioneering mass spectrometry research to enhance the detection and analysis of synthetic cannabinoids through radial electric field-driven collision-induced dissociation. This technique represents a significant advancement in forensic toxicology and pharmacology, enabling precise identification and quantification of complex substances (Ruan et al., 2023).
- Leukemia and Stem Cell Research: JWH-018 is studied for its potential therapeutic effects on leukemia and leukemic stem cells, offering a novel approach to cancer treatment. This research explores how synthetic cannabinoids can influence cancer pathogenesis and highlights possible applications in developing new cancer therapies (Salcin et al., 2024).
- Yeast Biosensor Development: Research on JWH-018 has contributed to the development of a yeast biosensor capable of cannabinoid detection. This biosensor is designed for biomedical and biotechnological applications, including point-of-use cannabinoid determination, demonstrating the versatility of JWH-018 in receptor research and drug testing (Miettinen et al., 2022).
- Comparative Pharmacology Studies: JWH-018 has been used in comparative studies of molecular signaling between synthetic cannabinoids and TRPV1 channel activation. These studies are crucial for understanding the pharmacological differences between various cannabinoids and their effects on the human body, providing insights into potential therapeutic uses and side effects (Andersen and Walsh, 2021).
- Drug Analysis in Blood Plasma: JWH-018 has also been part of research focused on enhancing drug analysis techniques in blood plasma. By developing non-fouling, sensitive surface-enhanced Raman scattering (SERS) substrates, researchers aim to improve the detection of potent drugs, including JWH-018, directly in complex biological matrices, which is essential for clinical diagnostics and forensic investigations (Masterson et al., 2021).
Legal Information
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
Storage Class
3 - Flammable liquids
wgk_germany
WGK 1
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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