Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

More Documents

857410P

Avanti

IG7

Avanti Research™ - A Croda Brand, powder

Synonym(s):

N-((2S,3R)-3-hydroxy-1-oxo-1-(tridecylamino)butan-2-yl)-5-methoxy-1H-indole-2-carboxamide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C27H43N3O4
CAS Number:
2132345-13-0
Molecular Weight:
473.65
UNSPSC Code:
12352211
NACRES:
NA.25

assay

99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (857410P-5mg)
pkg of 1 × 5 mg (857410P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

C[C@@H](O)[C@H](NC(C(N1)=CC2=C1C=CC(OC)=C2)=O)C(NCCCCCCCCCCCCC)=O

General description

IG7 is a ceramide analog.

Biochem/physiol Actions

IG7 is potent in enhancing Fas ligand (FasL) induced apoptosis in colon carcinoma cells SW480 and RKO. IG7 enhances FasL mediated phosphorylation of p38 and janus kinase (JNK). IG7 enhances nuclear factor-kappa B (NF-κB) activation by FasL. IG7 exhibits low toxicity.

Packaging

5ML Glass Amber Screw Cap Vial (857410P-1MG)
5ML Glass Amber Screw Cap Vial (857410P-5MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes
Coe GL, et al.
Scientific Reports, 6, 30816-30816 (2016)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service