810340P
Avanti
Click PI(4,5)P2-azido
Avanti Research™ - A Croda Brand 810340P, powder
Synonym(s):
1-oleoyl-2-(6-(6-azidohexanoyl)aminohexanoyl)-sn-glycero-3-phosphoinositol-4.5-bisphosphate (ammonium salt)
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About This Item
Recommended Products
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (with stopper and crimp cap (810340P-100ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 810340P
lipid type
click reagents
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is an anionic lipid and is present in the plasma membrane (PM).
Biochem/physiol Actions
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a lipid messenger. It controls exocytosis, actin cytoskeleton dynamics and endocytosis. It also plays a key role in signal transduction, vesicle trafficking and motility. The azido functional group in the lipid may involve in a copper-catalyzed reaction to form click reaction.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810340P-100ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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Journal of cell science, 128(22), 4047-4056 (2015-11-18)
Phosphoinositides are a collection of lipid messengers that regulate most subcellular processes. Amongst the seven phosphoinositide species, the roles for phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] at the plasma membrane, such as in endocytosis, exocytosis, actin polymerization and focal adhesion assembly, have been
Clickable lipids: azido and alkynyl fatty acids and triacylglycerols
Journal of the American Oil Chemists' Society, 86(11), 1115-1115 (2009)
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