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309923

Sigma-Aldrich

Ethyl nitrite solution

10-20 wt. % in ethanol

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About This Item

Linear Formula:
C2H5ONO
CAS Number:
109-95-5
Molecular Weight:
75.07
MDL number:
MFCD00010257
UNSPSC Code:
12352100
PubChem Substance ID:
24858758
NACRES:
NA.22

form

liquid

concentration

10-20 wt. % in ethanol

refractive index

n20/D 1.36

density

0.792 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CCON=O

InChI

1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3

InChI key

QQZWEECEMNQSTG-UHFFFAOYSA-N

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General description

The reactions of ethyl nitrite solution with human haemoglobin and sperm whale myoglobin were studied.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

59.0 °F - closed cup

flash_point_c

15 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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M P Doyle et al.
The Journal of biological chemistry, 256(23), 12399-12404 (1981-12-10)
The reactions of human hemoglobin and sperm whale myoglobin with ethyl nitrite under aerobic conditions have been examined in kinetic detail. Ethyl nitrite converts two equivalents of oxyhemoglobin or oxymyoglobin to their oxidized counterparts with concurrent production of one equivalent
Alessio Baccarani et al.
Journal of reconstructive microsurgery, 23(5), 257-262 (2007-09-19)
Vasospasm leading to thrombosis is a major cause of free flap failure. Flap blood flow may improve by application of vasodilating agents to the pedicle. The purpose of this study is to evaluate the effect of a novel S-nitrosylating agent
Basil M Yurcisin et al.
Annals of surgery, 257(5), 971-977 (2013-01-31)
To determine if reduction in nitric oxide bioactivity contributes to the physiological instability that occurs after brain death and, if so, to also determine in this setting whether administration of a renitrosylating agent could improve systemic physiological status. Organ function
Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.
Steven H Abman et al.
Lancet (London, England), 360(9350), 2076-2077 (2002-12-31)
Kazufumi Shimazutsu et al.
Clinical and translational science, 2(6), 405-412 (2010-05-07)
A method to maintain organ blood flow during laparoscopic surgery has not been developed. Here we determined if ethyl nitrite, an S-nitrosylating agent that would maintain nitric oxide bioactivity (the major regulator of tissue perfusion), might be an effective intervention
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