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VPS4A

vacuolar protein sorting 4 homolog A (S. cerevisiae)

Synonyms:
SKD1, SKD1A, SKD2, VPS4, VPS4-1
Species:
UniProtKB ID:
Gene ID:
  • Human(27183) Summary: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18. [provided by RefSeq, Jul 2008]
  • Mouse(116733) vacuolar protein sorting 4a (yeast)
  • Rat(246772) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • Zebrafish(767670) vacuolar protein sorting 4a (yeast)
  • domestic cat(101082613) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • dog(479674) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • chicken(425637) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • domestic guinea pig(100724580) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • naked mole-rat(101716007) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • Domestic Rabbit(100340140) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • cow(618168) vacuolar protein sorting 4 homolog A (S. cerevisiae)
  • sheep(101112669) vacuolar protein sorting 4 homolog A (S. cerevisiae)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VPS4A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-VPS4A, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-VPS4A Antibody, clone 14B1.1, clone 14B1.1, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-VPS4A (UT289), serum, from rabbit,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-VPS4A antibody, Mouse monoclonal, clone VPS4-110, purified from hybridoma cell culture,
Species Reactivity
bovine, canine, human, mouse, rat
Application
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Vps4a,
Species
mouse
MISSION® esiRNA, targeting human VPS4A, RP11-343C2.11,
Species
human