ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
Synonyms:
bHLHe1
Species:
Human ARNT2 (9915), Mouse Arnt2 (11864), Rat Arnt2 (25243), sheep ARNT2 (100135448), domestic guinea pig Arnt2 (100727525), naked mole-rat Arnt2 (101715821), Zebrafish arnt2 (64277), dog ARNT2 (608366), domestic cat ARNT2 (101087746), Horse ARNT2 (100067423) ...More
UniProtKB ID:
Gene ID:
- Human(9915) Summary: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Jul 2008]
- Mouse(11864) aryl hydrocarbon receptor nuclear translocator 2
- Rat(25243) aryl hydrocarbon receptor nuclear translocator 2
- sheep(100135448) aryl-hydrocarbon receptor nuclear translocator 2
- domestic guinea pig(100727525) aryl-hydrocarbon receptor nuclear translocator 2
- naked mole-rat(101715821) aryl-hydrocarbon receptor nuclear translocator 2
- Zebrafish(64277) aryl hydrocarbon receptor nuclear translocator 2
- dog(608366) aryl-hydrocarbon receptor nuclear translocator 2
- domestic cat(101087746) aryl-hydrocarbon receptor nuclear translocator 2
- Horse(100067423) aryl-hydrocarbon receptor nuclear translocator 2
- cow(533445) aryl-hydrocarbon receptor nuclear translocator 2
- chicken(415481) aryl-hydrocarbon receptor nuclear translocator 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ARNT2 antibody produced in mouse, clone 1B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-ARNT2 antibody produced in mouse, clone 3E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-ARNT2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence