1670207

Tolcapone

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): 3,4-Dihydroxy-4′-methyl-5-nitrobenzophenone, Ro 40-7592
• Wzór empiryczny (zapis Hilla): C₁₄H₁₁NO₅
• Numer CAS: 134308-13-7
• Masa cząsteczkowa: 273.24
• Numer MDL: MFCD00866569
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329751344
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• rodzina API: tolcapone
• producent / nazwa handlowa: USP
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• ciąg SMILES: Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)[N+]([O-])=O
• InChI: 1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
• Klucz InChI: MIQPIUSUKVNLNT-UHFFFAOYSA-N
• informacje o genach: human ... COMT(1312)

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Tolcapone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Tolcapone Tablets

Działania biochem./fizjol.

Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.

Komentarz do analizy

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Inne uwagi

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS09
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H400
• Zwroty wskazujące środki ostrożności: P273 - P391 - P501
• Klasyfikacja zagrożeń: Aquatic Acute 1
• Kod klasy składowania: 11 - Combustible Solids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable