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Merck

T4571

SAFC

Taurine

Produkcja farmaceutyczna

Synonim(y):

2-Aminoethanesulfonic acid

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About This Item

Wzór liniowy:
NH2CH2CH2SO3H
Numer CAS:
Masa cząsteczkowa:
125.15
Beilstein:
1751215
Numer WE:
Numer MDL:
Kod UNSPSC:
12352106
NACRES:
NA.26

pochodzenie biologiczne

non-animal source

Poziom jakości

Próba

≥98.5%

Postać

crystalline powder

metody

cell culture | mammalian: suitable

zanieczyszczenia

endotoxin, heavy metals, trace metals, tested

mp

>300 °C (lit.)

rozpuszczalność

H2O: ≥100 mg/mL

obecność zanieczyszczeń

cytotoxicity, tested

ciąg SMILES

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

Klucz InChI

XOAAWQZATWQOTB-UHFFFAOYSA-N

informacje o genach

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Opis ogólny

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Zastosowanie

Taurine is a derivative of the sulfur-containing (sulfhydryl) amino acid cysteine. Taurine is one of the few known naturally occurring sulfonic acids. It is a conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism. It can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Działania biochem./fizjol.

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves


Certyfikaty analizy (CoA)

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Takashi Ito et al.
Journal of molecular and cellular cardiology, 44(5), 927-937 (2008-04-15)
The sulfur-containing beta-amino acid, taurine, is the most abundant free amino acid in cardiac and skeletal muscle. Although its physiological function has not been established, it is thought to play an important role in ion movement, calcium handling, osmoregulation and
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The biosynthesis of bile acids by primary cultures of normal human hepatocytes has been investigated. A general and sensitive method for the isolation and analysis of sterols and bile acids was used, based on anion exchange chromatography and gas chromatography-mass
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