SRP5156

14-3-3 ζ, untagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Synonim(y): 14-3-3 ζ, KCIP-1, MGC111427, MGC126532, MGC138156, YWHAZ
• CAS Number: 1173938-18-5
• Kod UNSPSC: 12352202
• NACRES: NA.32

Właściwości

• pochodzenie biologiczne: human
• rekombinowane: expressed in E. coli
• Próba: ≥70% (SDS-PAGE)
• Formularz: buffered aqueous glycerol solution
• masa cząsteczkowa: ~29 kDa
• numer dostępu NCBI: NM_003406
• Zastosowanie: cell analysis
• Warunki transportu: dry ice
• temp. przechowywania: −70°C
• informacje o genach: human ... YWHAZ(7534)

Opis

Opis ogólny

14-3-3ζ (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3ζ protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis. 14-3-3ζ protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1.

Postać fizyczna

Supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Uwaga dotycząca przygotowania

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1