PHG0006

Guanidine hydrochloride

• Synonim(y): Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
• Wzór liniowy: NH₂C(=NH)NH₂ · HCl
• Numer CAS: 50-01-1
• Masa cząsteczkowa: 95.53
• Beilstein: 3591990
• Numer WE: 200-002-3
• Numer MDL: MFCD00013026
• Kod UNSPSC: 12352200
• NACRES: NA.21

Właściwości

• pochodzenie biologiczne: synthetic
• Poziom jakości: 400
• Postać: powder
• zanieczyszczenia: Endotoxin, microbial, and trace metals; tested
• pH: (25 °C, 4.6 - 6/573 g/L)
• mp: 180-185 °C (lit.)
• rozpuszczalność: H₂O: 6 M at 20 °C, clear, colorless
• gęstość: 1.3 g/cm³ (lit.)
• przydatność: suitable for manufacturing use
• obecność zanieczyszczeń: Dnase and RNase; tested
• ciąg SMILES: Cl[H].NC(N)=N
• InChI: 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
• Klucz InChI: PJJJBBJSCAKJQF-UHFFFAOYSA-N
• informacje o genach: human ... KCNA1(3736) , KCNA10(3744) , KCNA2(3737) , KCNA3(3738) , KCNA4(3739) , KCNA5(3741) , KCNA6(3742) , KCNA7(3743) , KCNB1(3745) , KCNB2(9312) , KCNC1(3746) , KCNC2(3747) , KCNC3(3748) , KCNC4(3749) , KCND1(3750) , KCND2(3751) , KCND3(3752) , KCNF1(3754) , KCNG1(3755) , KCNG2(26251) , KCNG3(170850) , KCNG4(93107) , KCNH1(3756) , KCNH2(3757) , KCNH3(23416) , KCNH4(23415) , KCNH5(27133) , KCNH6(81033) , KCNH7(90134) , KCNH8(131096) , KCNQ1(3784) , KCNQ2(3785) , KCNQ3(3786) , KCNQ4(9132) , KCNQ5(56479) , KCNS1(3787) , KCNS2(3788) , KCNS3(3790) , KCNV1(27012) , KCNV2(169522)

Opis

Opis ogólny

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Zastosowanie

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H302 + H332 - H315 - H319
• Zwroty wskazujące środki ostrożności: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable