PHR2589

Floxuridine

pharmaceutical secondary standard, certified reference material

• Synonim(y): 5-Fluoro-2′-deoxyuridine, 2′-Deoxy-5-fluorouridine, FUDR, Floxuridine
• Wzór empiryczny (zapis Hilla): C₉H₁₁FN₂O₅
• Numer CAS: 50-91-9
• Masa cząsteczkowa: 246.19
• Beilstein: 90221
• Numer MDL: MFCD00006530
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to USP 1271008
• opis: Pharmaceutical Secondary Standard; Certified Reference Material
• rodzina API: floxuridine
• Postać: powder
• Certyfikat analizy: current certificate can be downloaded
• opakowanie: pkg of 500 mg
• mp: 148 °C (lit.)
• Zastosowanie: pharmaceutical small molecule
• temp. przechowywania: 2-30°C
• ciąg SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
• Klucz InChI: ODKNJVUHOIMIIZ-RRKCRQDMSA-N

Opis

Opis ogólny

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Działania biochem./fizjol.

Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H301
• Zwroty wskazujące środki ostrożności: P264 - P270 - P301 + P310 - P405 - P501
• Klasyfikacja zagrożeń: Acute Tox. 3 Oral
• Kod klasy składowania: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Klasa zagrożenia wodnego (WGK): WGK 3