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Dokumenty

M1830000

Metoprolol tartrate

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

(±)-Metoprolol (+)-tartrate salt, (±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt, Lopressor

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About This Item

Wzór liniowy:
(C15H25NO3)2 · C4H6O6
Numer CAS:
56392-17-7
Masa cząsteczkowa:
684.81
Numer MDL:
MFCD00056257
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329817895
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

metoprolol

producent / nazwa handlowa

EDQM

metody

HPLC: suitable
gas chromatography (GC): suitable

Zastosowanie

pharmaceutical

format

neat

ciąg SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

Klucz InChI

YGULWPYYGQCFMP-CEAXSRTFSA-N

informacje o genach

human ... ADRB1(153)

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
This page may contain text that has been machine translated.

Piktogramy

Health hazardEnvironment
GHS08,GHS09

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H361d,H411

Zwroty wskazujące środki ostrożności

P202 - P273 - P280 - P308 + P313 - P391 - P405

Klasyfikacja zagrożeń

Aquatic Chronic 2 - Repr. 2

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Wenhuan Li et al.
Medicine, 93(28), e329-e329 (2014-12-20)
The sensitivity and specificity of 5 different image sets of dual-energy computed tomography (DECT) for the detection of first-pass myocardial perfusion defects have not systematically been compared using positron emission tomography (PET) as a reference standard. Forty-nine consecutive patients, with
Mehmet Ozaydin et al.
European heart journal, 34(8), 597-604 (2012-12-13)
Carvedilol and N-acetyl cysteine (NAC) have antioxidant and anti-inflammatory properties. Aim was to evaluate the efficacy of metoprolol, carvedilol, and carvedilol plus NAC on the prevention of post-operative atrial fibrillation (POAF). Patients undergoing cardiac surgery (n = 311) were randomized
Thomas Kahan et al.
European journal of clinical investigation, 43(2), 141-151 (2013-01-03)
Although stable angina pectoris often carries a favourable prognosis, it remains important to identify patients with an increased risk of cardiovascular (CV) complications. Many new markers of disease activity and prognosis have been described. We evaluated whether common and easily
C M Blake et al.
Clinical pharmacology and therapeutics, 94(3), 394-399 (2013-05-15)
Metoprolol, a commonly prescribed β-blocker, is primarily metabolized by cytochrome P450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity. Several smaller studies have shown that metoprolol pharmacokinetics is influenced by CYP2D6 genotype and metabolizer phenotype. To increase robustness of metoprolol
Martin H Ruwald et al.
Journal of the American College of Cardiology, 61(14), 1518-1526 (2013-03-19)
This study sought to compare the effects of metoprolol and carvedilol in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) study. The impact of beta-blockers in heart failure (HF) patients with devices is uninvestigated. All patients receiving
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