BP1083

Isoniazid

British Pharmacopoeia (BP) Reference Standard

• Synonim(y): 4-Pyridinecarboxylic acid hydrazide, INH, Isonicotinic acid hydrazide, Isonicotinic hydrazide
• Wzór empiryczny (zapis Hilla): C₆H₇N₃O
• Numer CAS: 54-85-3
• Masa cząsteczkowa: 137.14
• Beilstein: 119374
• Numer MDL: MFCD00006426
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• rodzina API: isoniazid
• Postać: powder
• okres trwałości: limited shelf life, expiry date on the label
• producent / nazwa handlowa: BP
• mp: 171-173 °C (lit.)
• Zastosowanie: pharmaceutical; pharmaceutical small molecule
• format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: NNC(=O)c1ccncc1
• InChI: 1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
• Klucz InChI: QRXWMOHMRWLFEY-UHFFFAOYSA-N

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Isoniazid BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Isoniazid Oral Solution

Działania biochem./fizjol.

Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations.

Opakowanie

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Inne uwagi

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H302,H315
• Zwroty wskazujące środki ostrożności: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• Klasyfikacja zagrożeń: Acute Tox. 4 Oral - Skin Irrit. 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3