556815

3-Ethyl-4-methyl-3-pyrrolin-2-one

97%

• Wzór empiryczny (zapis Hilla): C₇H₁₁NO
• Numer CAS: 766-36-9
• Masa cząsteczkowa: 125.17
• Numer MDL: MFCD00173861
• Kod UNSPSC: 12352100
• Identyfikator substancji w PubChem: 24879585
• NACRES: NA.22

Właściwości

• Próba: 97%
• mp: 100-104 °C (lit.)
• ciąg SMILES: CCC1=C(C)CNC1=O
• InChI: 1S/C7H11NO/c1-3-6-5(2)4-8-7(6)9/h3-4H2,1-2H3,(H,8,9)
• Klucz InChI: YCTNTSVMJWIYTQ-UHFFFAOYSA-N

Opis

Opis ogólny

3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:

• allylamine, via palladium(II)-assisted cyclization
• 4-methoxybenzylamine, via a ring-closing-metathesis strategy
• 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one

Zastosowanie

3-Ethyl-4-methyl-3-pyrrolin-2-one (3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one) may be employed as a precursor for the synthesis of glimepiride (antidiabetic drug) and its derivatives (sulfonylurea drugs). It may also be employed for the preparation of 2-ethyl-3-methyl-(10H)-
dipyrrin-1-one.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)