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ZP2

zona pellucida glycoprotein 2 (sperm receptor)

Synonimy:
ZPA, Zp-2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(7783) Summary: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. [provided by RefSeq, Jul 2008]
  • Mouse(22787) zona pellucida glycoprotein 2
  • Rat(81828) zona pellucida glycoprotein 2 (sperm receptor)
  • Domestic Rabbit(100009069) zona pellucida glycoprotein 2 (sperm receptor)
  • naked mole-rat(101706160) zona pellucida glycoprotein 2 (sperm receptor)
  • domestic guinea pig(100713508) zona pellucida glycoprotein 2 (sperm receptor)
  • cow(280963) zona pellucida glycoprotein 2 (sperm receptor)
  • sheep(101123598) zona pellucida glycoprotein 2 (sperm receptor)
  • chicken(427006) zona pellucida glycoprotein 2 (sperm receptor)
  • dog(403988) zona pellucida glycoprotein 2 (sperm receptor)
  • domestic cat(493977) zona pellucida glycoprotein 2 (sperm receptor)

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ZP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-ZP2 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Monoclonal Anti-ZP2 antibody produced in mouse, clone 2B9, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-ZP-2 Antibody, clone IE-3, clone IE-3, from rat,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Zp2,
Gatunek
mouse
MISSION® esiRNA, targeting human ZP2,
Gatunek
human