VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
Synonimy:
NR1I1
Gatunek:
Human VDR (7421), Mouse Vdr (22337), Rat Vdr (24873), chicken VDR (395988), dog VDR (486588), Horse VDR (100034072), domestic cat VDR (100316614), cow VDR (533656), sheep VDR (101107273), sheep VDR (100294603) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
- Mouse(22337) vitamin D receptor
- Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
- chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor
- dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
- Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
- domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
- cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
- sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
- sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
- naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
- domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor
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Small Molecule - Agonist
Numer produktu
Opis
Gatunek
Vitamin D2 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Vitamin D3 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-VDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
western blot
Anti-phospho-Vitamin D Receptor (pSer208) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
immunohistochemistry
Anti-Vitamin D3 Receptor Antibody, clone 1M19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
bovine, canine, feline, human, monkey, mouse, porcine, rat
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
esiRNA
Numer produktu
Opis
Gatunek