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TLR7

toll-like receptor 7

Synonimy:
TLR7-like
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • dog(491743) toll-like receptor 7

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Imiquimod, ≥98% (HPLC), solid,
Gatunek
human
Imikwimod, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Hydroksychlorochina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Hydroxychloroquine sulfate, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Hydroxychloroquine sulfate, analytical standard,
Gatunek
human
Hydroxychloroquine sulfate, ≥98% (HPLC), powder,
Gatunek
human
Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Mysz anty-TLR7 mAb (2C9), liquid, clone 2C9, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
Przeciwciało anty-TLR7, klon 3G6S4, królicze monoklonalne, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunocytochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TLR7,
Gatunek
human
MISSION® esiRNA, targeting mouse Tlr7,
Gatunek
mouse