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TLR7

toll-like receptor 7

Synonimy:
TLR7-like
Gatunek:
Human TLR7 (51284), Mouse Tlr7 (170743), Rat Tlr7 (317468), cow TLR7 (493686), sheep TLR7 (554254), Goat TLR7 (100860934), naked mole-rat Tlr7 (101705918), domestic guinea pig Tlr7 (100713329), Zebrafish tlr7 (100534776), Horse TLR7 (791248) ...Więcej
Identyfikator UniProtKB:
Q9NYK1, D1CS69, Q9NR98
Identyfikator genu:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • dog(491743) toll-like receptor 7

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
1338313
Imikwimod, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
I5159
Imiquimod, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
BP1101
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
TMT00427
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Gatunek
human
1327000
Hydroksychlorochina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
BP1100
Hydroxychloroquine sulfate, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
90527
Hydroxychloroquine sulfate, analytical standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
PRS3269
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunocytochemistry
western blot
HPA059613
Anti-TLR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
SAB5702076
Przeciwciało anty-TLR7, klon 3G6S4, królicze monoklonalne, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
AP1181
Mysz anty-TLR7 mAb (2C9), liquid, clone 2C9, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie
SAB1409406
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA

esiRNA

Numer produktu
Opis
Gatunek
EMU015751
MISSION® esiRNA, targeting mouse Tlr7,
Gatunek
mouse
EHU011031
MISSION® esiRNA, targeting human TLR7,
Gatunek
human