SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Synonimy:
ASV, SRC1, c-SRC, p60-Src
Gatunek:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), cow SRC (535742), sheep SRC (101103084), naked mole-rat Src (101703827), domestic guinea pig Src (100728509), Zebrafish src (325084), domestic cat SRC (101100378), dog SRC (485864)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(20779) Rous sarcoma oncogene
- Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
- cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- domestic guinea pig(100728509) Rous sarcoma oncogene
- Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- chicken(396442) v-src sarcoma viral oncogene
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Small Molecule - Antagonist
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Antibodies
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Zastosowanie
Przeciwciało anty-fosfo-SRC-Y529produkowane u królików, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anty-Src, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
western blot
Przeciwciało przeciwko acetylowanemu Src (Lys430), from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
cell based assay
western blot
western blot
Przeciwciało anty-fosfo-Src (Tyr416), klon 2N8, królicze monoklonalne, clone 2N8, Upstate®, from rabbit,
Reaktywność gatunkowa
mouse, vertebrates
Zastosowanie
western blot
Przeciwciało anty-fosfo-Src (Tyr416), klon 9A6, clone 9A6, Upstate®, from mouse,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
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Kits
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Proteins
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Białko Src (T341M), aktywne, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Gatunek
human
Białko Src, aktywne, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Gatunek
human
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
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human
esiRNA
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Small Molecule - Substrate
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