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Merck

RARB

retinoic acid receptor, beta

Synonimy:
HAP, NR1B2, RRB2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5915) Summary: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(218772) retinoic acid receptor, beta
  • Rat(24706) retinoic acid receptor, beta
  • Domestic Rabbit(100358445) retinoic acid receptor, beta
  • naked mole-rat(101724485) retinoic acid receptor, beta
  • domestic guinea pig(100379264) retinoic acid receptor, beta
  • cow(616895) retinoic acid receptor, beta
  • sheep(101122663) retinoic acid receptor, beta
  • chicken(396266) retinoic acid receptor, beta
  • Horse(100051546) retinoic acid receptor, beta
  • domestic cat(101085742) retinoic acid receptor, beta
  • dog(477045) retinoic acid receptor, beta

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Small Molecule - Activator

Numer produktu
Opis
Gatunek
9-cis-Retinoic acid, ≥98% (HPLC),
Gatunek
human
Retinoic acid, ≥98% (HPLC), powder,
Gatunek
mouse, human

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
AM580, ≥98% (HPLC),
Gatunek
human
Tretynoina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Tretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Isotretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Tretinoin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
AM580, ≥98% (HPLC),
Gatunek
human
CD437, ≥98% (HPLC), solid,
Gatunek
human
TTNPB, ,
Gatunek
human
Retinoic acid, ≥98% (HPLC), powder,
Gatunek
mouse, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Retinoic Acid Receptor β, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-RARB antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, horse, human, mouse, pig, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-RARβ, klon 6D5V4, królicze monoklonalne, ,
Reaktywność gatunkowa
mouse
Zastosowanie
immunofluorescence
western blot

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
TTNPB, ,
Gatunek
human
9-cis-Retinoic acid, ≥98% (HPLC),
Gatunek
human
Retinoic acid, ≥98% (HPLC), powder,
Gatunek
mouse, human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
Retinoic acid, ≥98% (HPLC), powder,
Gatunek
mouse, human

Proteins

Numer produktu
Opis
Gatunek
RAR, β human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE),
Gatunek
human
RAR β-ligand binding domain (173-409) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human
RARβ, ligand binding domain (173-409), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Rarb,
Gatunek
mouse
MISSION® esiRNA, targeting human RARB,
Gatunek
human