POLG
polymerase (DNA directed), gamma
Synonimy:
MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE
Gatunek:
Human POLG (5428), Mouse Polg (18975), Rat Polg (85472), naked mole-rat Polg (101700433), domestic guinea pig Polg (100728907), cow POLG (533090), sheep POLG (101123414), Zebrafish polg (100150924), dog POLG (488732), chicken POLG (404292) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(5428) Summary: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18975) polymerase (DNA directed), gamma
- Rat(85472) polymerase (DNA directed), gamma
- naked mole-rat(101700433) polymerase (DNA directed), gamma
- domestic guinea pig(100728907) polymerase (DNA directed), gamma
- cow(533090) polymerase (DNA directed), gamma
- sheep(101123414) polymerase (DNA directed), gamma
- Zebrafish(100150924) polymerase (DNA directed), gamma
- dog(488732) polymerase (DNA directed), gamma
- chicken(404292) polymerase (DNA directed), gamma
- domestic cat(101083771) polymerase (DNA directed), gamma
- Horse(100053827) polymerase (DNA directed), gamma
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-DNA Polymerase gamma Antibody, clone 9V9D9, Rabbit Monoclonal, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-DNA polymerase subunit gamma-1 Antibody/POLG, 1.0 mg/mL, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)
immunoprecipitation (IP)