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POLD2

polymerase (DNA directed), delta 2, accessory subunit

Synonimy:
Gatunek:
Human POLD2 (5425), Mouse Pold2 (18972), Rat Pold2 (289758), Thale Cress POLD2 (818812), Zebrafish pold2 (796456), domestic cat POLD2 (101095089), dog POLD2 (482686), chicken POLD2 (100859398), cow POLD2 (281991), sheep POLD2 (101117838) ...Więcej
Identyfikator UniProtKB:
P49005
Identyfikator genu:
  • Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
  • Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
  • Thale Cress(818812) DNA polymerase delta subunit 2
  • Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit
  • domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
  • dog(482686) polymerase (DNA directed), delta 2, accessory subunit
  • chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
  • cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
  • domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
  • naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
  • Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4200054
Anti-DNA polymerase δ p50 antibody, Rat monoclonal, clone PDK 7B4, purified from hybridoma cell culture,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)
western blot
HPA026745
Anti-POLD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
SAB1410988
Anti-POLD2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Product Number
Opis
Gatunek
PHR1787
Cytarabine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
C3350000
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
C6645
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Gatunek
human
1162002
Cytarabina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
BP383
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
EHU159311
MISSION® esiRNA, targeting human POLD2,
Gatunek
human
EMU049531
MISSION® esiRNA, targeting mouse Pold2,
Gatunek
mouse